Atorvastatin is indicated as an adjunct to diet for reduction of elevated total cholesterol, LDL-cholesterol, apolipoprotein B, and triglycerides in patients with-
- Primary hypercholesterolemia- heterozygous familial and non-familial hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb)
- Elevated serum TG levels (Fredrickson type IV)
- Primary dysbetalipoproteinemia (Fredrickson type III) who do not respond adequately to diet.
- Homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (LDL apheresis) or if such treatments are unavailable.
Dosage & Administration
Children: Treatment experience in a paediatric population with dose of Atorvastatin up to 80 mg/day is limited.
Geriatric (>70 years): The safety and efficacy of Atorvastatin in this population is as similar as < 70 years of age patients with the dose upto 80 mg/day.
In patients with Renal Insufficiency: No dosage adjustment is required.