Monosulfiram solution is a parasiticide, active against the burrowing mite Sarcoptes scabiei. It is indicated for the treatment and prophylaxis of scabies.
Monosulfiram, is an ectoparasiticide used in the treatment and prevention of scabies.
Dosage & Administration
Before application Monosulfiram Solution should be diluted with two to three parts of water. The patient’s body should be liberally washed with soap and water and thoroughly dried. Apart from face and scalp, the entire body should be painted with the dilute solution, which is rubbed well in and left to dry. About ten minutes is allowed for the skin to dry naturally and the patient then dresses. Application is suitable for use in clinics dealing with children. In difficult cases this routine may be repeated successively for two or three days. These instructions are applicable to adults and children.
There are no known drug interactions and none well documented.
Known idiosyncratic response to its application. The solution should not be applied near a naked flame. Because of the close chemical relationship between monosulfiram and disulfiram, it is advisable to abstain from alcohol before and for at least 48 hours after the application of Monosulfiram
Very few side-effects occur with Monosulfiram Solution even in cases of undiluted application. A few cases of erythematous rash considered as idiosyncratic response have been reported.
Pregnancy & Lactation
Pregnancy Category is not Classified. FDA has not yet classified the drug into a specified pregnancy category.