Description: Neurocare® is a preparation of Thiamine Mononitrate (Vitamin B1), Pyridoxine
Hydrochloride (Vitamin B6) & Cyanocobalamin (Vitamin B12) tablet. These vitamins play an
essential role as co-enzyme in the metabolism of the nervous system. The combination of these
three vitamins show better effect than that of the individual component. Thus, this tablet is used
as the logical and scientific treatment of nerve degeneration, its associated symptoms and as an
adjuvant with NSAIDs to potentiate their analgesic effect with reduced treatment time and lesser
Indications: It is indicated in polyneuropathy of any origin such as Diabetic, Alcoholic or Toxic
neuropathies, Neuritis, Neuralgia, Cervical Syndrome, Shoulder-arm syndrome, Lumbago,
Sciatica, Herpes Zoster, Trigeminal Neuralgia and Supportive treatment in facial paresis.
Dosage and Administration: This tablet may be administered in a dosage of 1 to 3 tablets daily
or as per the direction of physicians.
Contraindications: It should not be used in patients on Levodopa therapy and hypersensitivity to
any of the above vitamins.
Precautions: Cyanocobalamin should not be given before a diagnosis has been fully established
because of the possibility of masking symptoms of subacute degeneration of the spinal cord.
Cyanocobalamin is not a suitable form of Vitamin B12 for the treatment of optic neuropathies
associated with raised plasma concentrations of cyanocobalamin.
Adverse Reactions: Allergic hypersensitivity reactions may occur.
Use in Pregnancy & Lactation: Neurocare® is safe for pregnant women. It is not known whether
Vitamin B1 is excreted in breast milk or not, but may be taken cautiously during lactation. Vitamin
B6 has no adverse effect during lactation. There is no known adverse effect on Vitamin B12
Drug Interactions: Pyridoxine Hydrochloride reduces the effects of levodopa. It also interacts
with phenobarbital, isoniazide and oral contraceptive. Absorption of cyanocobalamin from
gastrointestinal tract may be reduced by neomycin, aminosalicylic acid, and H2-receptor
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