Ezex® preparations are indicated for the treatment of eczema and dermatitis of all types including atopic eczema, photodermatitis, otitis externa, primary irritant allergic dermatitis (including napkin rash), intertrigo, prurigo nodularis, seborrhoeic dermatitis and insect bite reactions.
Ezex® may be used as a maintenance therapy between courses of one of the more active topical steroids.
DOSAGE AND ADMINISTRATION
Apply to the affected area up to four times a day until improvement occurs, when the frequency of application may be reduced.
CONTRAINDICATION AND PRECAUTION
Skin lesions caused by infection with viruses (e.g. herpes simplex, chicken pox), fungi (e.g. candidiasis, tinea) or bacteria (e.g. impetigo), hypersensitivity to the preparations.
Although generally regarded as safe, even for long-term administration in adults, there is a potential for overdosage, and in infants and children this may result in adrenal suppression. Extreme caution is required in
dermatoses in such patients including napkin eruption (as the napkin may act as an occlusive dressing and increase absorption) and treatment should not normally exceed seven days.
In the unlikely event of signs of hypersensitivity appearing, application should stop immediately. When large areas of the body are being treated with Clobetasone Butyrate, it is possible that some patients will absorb
sufficient steroid to cause transient adrenal suppression despite the low degree of systemic activity associated with Clobetasone Butyrate.
Local atopic changes could possibly occur in situations where moisture increases absorption of Clobetasone Butyrate, but only after prolonged use.
There are reports of pigmentation changes and hypertrichosis with topical steroids.
Exacerbation of symptoms may occur